Karim Fizazi Selected Research

Estramustine

12/2020	Long-term Castration-related Outcomes in Patients With High-risk Localized Prostate Cancer Treated With Androgen Deprivation Therapy With or Without Docetaxel and Estramustine in the UNICANCER GETUG-12 Trial.
1/2016	Outcome According to Elective Pelvic Radiation Therapy in Patients With High-Risk Localized Prostate Cancer: A Secondary Analysis of the GETUG 12 Phase 3 Randomized Trial.
7/2015	Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial.
1/2012	A phase III trial of docetaxel-estramustine in high-risk localised prostate cancer: a planned analysis of response, toxicity and quality of life in the GETUG 12 trial.
12/2011	The use of estramustine phosphate in the modern management of advanced prostate cancer.
5/2009	Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer.
11/2007	Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data.
9/2004	High efficacy of docetaxel with and without androgen deprivation and estramustine in preclinical models of advanced prostate cancer.

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Karim Fizazi Research Topics

Disease

221	Prostatic Neoplasms (Prostate Cancer) 10/2022 - 03/2002
74	Neoplasms (Cancer) 07/2022 - 02/2002
59	Neoplasm Metastasis (Metastasis) 02/2022 - 03/2002
37	Pain (Aches) 07/2022 - 03/2003
25	Disease Progression 01/2022 - 06/2014
16	Fatigue 03/2022 - 01/2012
13	Seminoma 01/2022 - 08/2003
13	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 10/2021 - 10/2004
12	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 07/2003
9	Hypertension (High Blood Pressure) 01/2022 - 05/2011
7	Circulating Neoplastic Cells 01/2020 - 01/2016
6	Febrile Neutropenia 01/2022 - 02/2013
6	Asthenia 01/2022 - 04/2015
6	Neutropenia 01/2022 - 02/2013
6	Bone Resorption 01/2013 - 07/2003
6	Carcinoma (Carcinomatosis) 07/2009 - 10/2002
5	Breast Neoplasms (Breast Cancer) 06/2022 - 04/2009
5	Edema (Dropsy) 03/2022 - 11/2012
5	Nausea 01/2022 - 05/2013
4	Pneumonia (Pneumonitis) 01/2022 - 04/2015
4	Diarrhea 10/2021 - 09/2012
4	Testicular Neoplasms (Testicular Cancer) 01/2021 - 08/2011
4	Kidney Neoplasms (Kidney Cancer) 01/2020 - 04/2014
3	Cancer Pain 01/2022 - 01/2013
3	Adenocarcinoma 01/2021 - 12/2007
3	Hypocalcemia 02/2019 - 02/2014
3	Osteonecrosis (Kienbock's Disease) 02/2019 - 01/2012
3	Seizures (Absence Seizure) 01/2019 - 09/2012
3	Hypokalemia 01/2018 - 05/2011
3	Urinary Bladder Neoplasms (Bladder Cancer) 10/2016 - 07/2006

Drug/Important Bio-Agent (IBA)

61	Docetaxel (Taxotere)FDA Link 03/2022 - 09/2004
56	AndrogensIBA 02/2022 - 03/2002
38	Prostate-Specific Antigen (Semenogelase)IBA 01/2022 - 07/2003
36	enzalutamideIBA 03/2022 - 09/2012
36	Prednisone (Sone)FDA LinkGeneric 02/2022 - 05/2011
34	Abiraterone AcetateIBA 02/2022 - 05/2011
28	abirateroneIBA 01/2022 - 05/2011
27	Hormones (Hormone)IBA 10/2022 - 10/2008
24	Androgen Receptors (Androgen Receptor)IBA 02/2022 - 03/2002
17	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 02/2002
16	cabazitaxel FDA Link 03/2022 - 06/2014
16	Denosumab FDA Link 02/2019 - 04/2009
14	darolutamideIBA 07/2022 - 08/2014
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2010
11	Pharmaceutical PreparationsIBA 01/2022 - 07/2003
10	taxaneIBA 06/2022 - 01/2010
10	Poly(ADP-ribose) Polymerase InhibitorsIBA 05/2022 - 01/2020
10	Diphosphonates (Bisphosphonates)IBA 02/2016 - 04/2009
8	Estramustine FDA Link 12/2020 - 09/2004
8	Zoledronic Acid (Zometa)FDA Link 02/2019 - 03/2011
7	AntigensIBA 10/2022 - 05/2015
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
7	IpilimumabIBA 01/2021 - 06/2014
7	collagen type I trimeric cross-linked peptideIBA 09/2015 - 04/2009
7	Monoclonal AntibodiesIBA 07/2015 - 04/2009
6	Etoposide (VP 16)FDA LinkGeneric 01/2022 - 10/2002
6	Carboplatin (JM8)FDA LinkGeneric 01/2022 - 12/2006
6	Immune Checkpoint InhibitorsIBA 01/2022 - 10/2017
6	Alkaline PhosphataseIBA 01/2020 - 01/2013
5	Taxoids (Taxanes)IBA 03/2022 - 06/2013
5	olaparibIBA 01/2022 - 01/2020
5	TabletsIBA 01/2022 - 01/2016
5	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2021 - 12/2002
5	Biological ProductsIBA 06/2021 - 12/2002
5	Testosterone (Sustanon)FDA Link 12/2020 - 08/2014
5	RadiopharmaceuticalsIBA 01/2020 - 05/2009
5	Androgen Receptor AntagonistsIBA 10/2019 - 12/2017
4	PlacebosIBA 02/2022 - 01/2018
4	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2020 - 01/2013
4	Hemoglobins (Hemoglobin)IBA 01/2020 - 07/2015
4	Radium-223IBA 01/2019 - 11/2015
4	Gemcitabine FDA Link 01/2019 - 09/2003
4	CreatinineIBA 09/2015 - 04/2009
4	Endothelins (Endothelin)IBA 05/2013 - 07/2003
3	talazoparibIBA 06/2022 - 01/2021
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2022 - 01/2020
3	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2022 - 01/2016
3	antiarrhythmic peptide (AAP)IBA 02/2022 - 11/2018
3	NivolumabIBA 01/2022 - 10/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2018
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 10/2019
3	Opiate AlkaloidsIBA 01/2022 - 01/2013
3	rucaparibIBA 12/2021 - 01/2020
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2020 - 02/2013
3	cabozantinibIBA 01/2020 - 01/2016
3	Everolimus FDA Link 12/2017 - 12/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2017 - 01/2013
3	alpha-Fetoproteins (alpha-Fetoprotein)IBA 02/2016 - 10/2004
3	sipuleucel-T (APC8015)FDA Link 11/2015 - 05/2015
3	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 12/2014 - 08/2003
3	RANK LigandIBA 10/2013 - 07/2003
3	ZD4054IBA 05/2013 - 07/2012

Therapy/Procedure

171	Castration 07/2022 - 03/2002
113	Therapeutics 10/2022 - 03/2003
88	Drug Therapy (Chemotherapy) 06/2022 - 02/2002
21	Radiotherapy 01/2022 - 08/2003
7	Aftercare (After-Treatment) 01/2022 - 05/2009
6	Immunotherapy 01/2020 - 12/2006
4	Precision Medicine 06/2021 - 01/2014
4	Duration of Therapy 11/2020 - 10/2011